Biologicals are pharmaceutical products that contain proteins that originate from biotechnology and work as active substances.
Throughout the years, a large number of different biomolecules and their roles in different biochemical processes have been researched. This has resulted in many different types of biologicals for different applications in the field of therapeutic and medical diagnostics.
These can be classified into the following groups, but are certainly not limited to them.
- Plasma-fractionated products
- Monoclonal antibodies (mAbs)
- Recombinant proteins
The production processes of most biologicals consist of four major contiguous parts, namely: cell culture and fermentation, harvesting and determination, purification, aseptic filling and finishing.
M-filter offers a very broad range of microfiltration products for media preparation, sterile venting, clarification of the cell harvest, reduction of biological load and sterilisation of different liquid flows in both the upstream and downstream processes.
|Mammalian Cell Culture|
|Harvesting and Clarification|
|Mammalian Cell Culture Clarification|
|Microbial fermentation Broth Clarification|
|Aseptic filling and finishing|
|Sterilisation of buffer|
|Sterilisation of product|
|Sterilisation or air/gases|